Sweet bee venom pharmacopuncture for chemotherapy-induced peripheral neuropathy
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular energy metabolism
The mitogen-activated protein kinases (MAPKs) family, including extracellular signal-regulated kinase 1/2 (ERK1/2), p38 MAPK, and c-Jun NH2-terminal kinase (JNK1/2), has been shown to play a significant role in the mediation of signals triggered by cytokines, growth factors, and environmental stress and is involved in various cellular functions [9, 10]
However, data from the CDC in 2025 indicates a shift, with the prevalence now estimated at 1 in 31 children in the U.S., reflecting a slight decrease in the rate of diagnosis (Shaw et al