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Eur J Pharmacol 928(11):175096

In the first stage, titles and abstracts of articles retrieved from databases such as PubMed and Google Scholar were screened

For long-term use spanning more than one year, 12 weeks on followed by 8 weeks off is the advised structure to minimize cumulative receptor desensitization

In another phase I trial of CB-839 and paclitaxel in triple negative breast cancer, patients receiving CB-839 and paclitaxel showed different extents of improvement from disease control to partial response with tolerable adverse effects [64]