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Bioscience, Biotechnology, and Biochemistry, 66 (6), 14311434
Garlic plants ( Allium sativum ) produce volatile organosulfur compounds, such as diallyl thiosulfinate (allicin) and diallyl polysulfanes, which are known for their antimicrobial, antiviral, anticancer, anti-inflammatory and immunomodulatory effects ( Allicin is a thiol-reactive compound, which reacts with Cys thiols via thiol-disulfide exchange reactions, leading to S -thioallylations of proteins ( S -thioallylations of redox-sensitive Cys residues in proteins were identified in the proteome of human Jurkat cells, Escherichia coli , Staphylococcus aureus , and Bacillus subtilis ( S -thioallylated proteins were identified 10 min after allicin treatment, including highly abundant cytoskeleton proteins, HSP90 chaperones, translation elongation factors and glycolytic enzymes
MACS is still treatable with the same strategies and targeted treatments Dr
Erkekoglu P, Baydar T (2014) Acrylamide neurotoxicity
