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Coenzyme for enzymatic glutathione peroxidases (metalloenzymes)

Its also worth noting that Novo Nordisk isnt the only company interested in amylin-based approachesRoche and Zealand Pharma are developing a separate amylin analog called petrelintide, underscoring the broader industry interest in this pathway

Furthermore, Erastin-induced ferroptosis in target cells is accompanied by membrane rupture and the release of large amounts of ROS, which may further enhance autophagy via ROS-mediated activation of the AMPK/mTOR signaling pathway

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