The selenoprotein family of iodothyronine deiodinases consists of three enzymes, D1, D2 and D3, which are specifically distributed in tissues and regulate the activation and inactivation of TH: type 1 and 2 deiodinases (D1/D2) catalyse the conversion of the inactive precursor thyroxine (T4) to the active form, triiodothyronine (T3), while type 3 deiodinases (D3) terminate the hormones action by degradation ( 5 Hcy and thyroid diseases 5.1 Hcy and thyroid nodules In recent decades, with the widespread availability of ultrasound technology, thyroid nodules have become a common clinical disease
Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or References Roofthooft DW, Simons SH, Anand KJ et al , Eight years later are we still hurting newborn infants
Metabolic coordination of cell fate by -ketoglutarate-dependent dioxygenases
Furthermore, clinical studies are also encouraging a randomized, double-blind, controlled trial conducted with 75 bipolar disorder patients for 24 weeks
