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Consequently, inhibiting ACSL4 expression represents an important direction in ferroptosis research ( The final step of PUFA-PE peroxidation requires lipoxygenase catalysis, suggesting a potential role for these enzymes in ferroptosis induction

2013;8:e63388

In biochemical and cellular research systems, Vitamin B-12dependent enzymes such as methionine synthase and methylmalonyl-CoA mutase are studied for their roles in DNA synthesis, amino acid metabolism, and fatty acid processing