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[111] At sufficiently high doses, somnolence (sleepiness or drowsiness), confusion, syncope (loss of consciousness from fainting), shortness of breath, marked weakness, seizures, and coma may occur

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It's able to give the user a quicker effect and the nicotine rush feeling typically felt from traditional cigarettes, and what some users say they are missing from the "freebase" nicotine ejuice

Tobacco cessation strategies should be individualised and may include behavioural support, nicotine replacement therapy (NRT), or pharmacological interventions