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PLoS ONE 8 , e72533 (2013)

As part of the office visit, your doctor will take a complete medical history, including asking you about: Your general health Medications you take Your joint pain and other symptoms when they started and whether the symptoms have changed over time Whether you or any family member has a history of arthritis or any autoimmune disorders Physical Examination During the physical examination, your doctor will look for: Signs of RA, including swollen or tender joints, limitation of joint motions, and early deformity

doi: 10.3390/ijms23105354 279

In fact, there has been a steady increase in the incidence of acetaminophen-related toxicity over the past decade