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(ii) the release of proinflammatory cytokines contributes to cell loss

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Research indicates that the levels of reactive oxygen species (ROS) in synovial fluid are significantly higher in RA patients than in healthy individuals, highlighting the important role of oxidative stress in the progression of RA

The networks showed that the major potential targeting pathways of (-)-Vestitol included Neuroactive ligand-receptor interaction pathway, Calcium signaling pathway, Metabolic pathways, Alzheimer disease, Estrogen signaling pathway, PI3K-Akt signaling pathway, and Immune system