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The ice shell is predicted to be between 20 and 30 km thick (Howell, 2021), which would correspond to a pressure at the ice-ocean interface of approximately 20 to 30 MPa (Hand et al., 2006

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10.1016/j.bmcl.2017.07.013 Summary Keywords docking, MD simulations, pharmacophore, acetylcholinesterase, machine learning Citation Hayek-Orduz Y, Acevedo-Castro DA, Saldarriaga Escobar JS, Ortiz-Domnguez BE, Villegas-Torres MF, Caicedo PA, Barrera-Ocampo , Cortes N, Osorio EH and Gonzlez Barrios AF (2025) dyphAI dynamic pharmacophore modeling with AI: a tool for efficient screening of new acetylcholinesterase inhibitors

Complementary NAD+ replacement strategies fail to functionally protect dystrophin-deficient muscle