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BrusqJ-MAncellinNGrondinPGuillardRMartinSSaintillanYet alInhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine

The synergistic effect of aromatic residues, arginine and negatively charged histidine can enhance the stability of enzyme binding, and the regulation of hydrophobic N-terminal residues on aging-related enzyme activities reveals a new optimization direction

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