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Discussion: Overall, our data revealed that ENDS exposure exacerbates features of COPD in bENaC mice including emphysema, mucus accumulation, abnormal lung inflammation, and fibrosis, which involves the effect of COPD development by inducing ferroptosis in the lung

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This measure is intended to encourage a level playing field in the ENDS market

Regarding the role of PRS in never-smokers, our results suggest that their incident risk did not achieve statistical significance as the PRS group increased