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To make sure their findings werent accounting for cigarette smokers switching to e-cigarettes specifically because of existing health issues (rather than the vaping itself causing these issues), the researchers only included people in the study who reported having no respiratory issues when they entered PATH, adjusting for a comprehensive set of health conditions

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E-cigarette aerosol can contain: highly addictive nicotine that can harm brain development ultrafine toxic particles that can interfere with the growth and work of the lungs and increase the risk of heart disease, lung cancer, and asthma attacks harmful heavy metals such as lead, tin, and nickel volatile organic compounds that can cause long-term health effects including cancer

Even the liver can grow back sometimes if a portion of it is removed