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Thus, the concentration of homocysteine in the blood is regulated by three B-vitamins: folate, vitamin B 12 , and vitamin B 6 (4)

The peptide also appears to interact with pain signaling pathways in the central nervous system, offering relief from both inflammatory and non-inflammatory pain

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Injection of substance P (SP) N-terminal fragment SP(1-7) into the ventral tegmental area modulates the levels of nucleus accumbens dopamine and dihydroxyphenylacetic acid in male rats during morphine withdrawal