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The gut microbiota is considered an environmental factor that regulates host metabolism by interacting with different tissues via microbiota-derived signals and metabolites [78]

Key Takeaways GHK-Cu is a copper binding tripeptide, not a hormone It modulates extracellular matrix remodeling Its effects are local rather than endocrine Human evidence supports skin and wound applications Systemic anti aging claims exceed available data Sources Pickart L, Thaler MM

Conclusions are moderated by the paucity of research for many herbs, the variation in dosages and extracts used, small sample sizes, and the heterogeneity of study characteristics