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(2022b) looked at how the administration of levodopa-carbidopa intestinal gel (LCIG) has effects on the gut microbiome in PD

Moreover, chronic oxidative stress generated through CYP2E1 induction was shown to interfere with the insulin signaling cascade via a decrease in tyrosine phosphorylation of insulin receptor substrates 1 and 2

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Iron Metabolism and Ferroptosis Iron homeostasis is controlled in cells and systems, such as to provide the iron needed for cells and tissues, thereby avoiding iron overload and iron-related toxicity (Piperno et al., 2020)