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5 mg/mL concentration: 50 units = 2.5 mg (starting dose, weeks 1-4) 10 mg/mL concentration: 50 units = 5 mg (moderate dose, weeks 5-8) 15 mg/mL concentration: 50 units = 7.5 mg (mid-range dose, weeks 9-12) 17 mg/mL concentration: 50 units = 8.5 mg (between standard tiers) 20 mg/mL concentration: 50 units = 10 mg (high dose, weeks 13-16) 30 mg/mL concentration: 50 units = 15 mg (maximum dose, week 21+) Notice the pattern

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When to Seek Medical Attention : Severe allergic reaction (itching, swelling, difficulty breathing) Chest pain or sudden weakness Drug Interactions : Can interfere with certain laboratory tests and may interact with medications like folic acid, requiring monitoring in some cases