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In the AMY 1 R and AMY 3 R Y37 rAmy interacts with residues in the respective RAMP and the CTR ECD, however the small side chain of P37 Cagri is completely buried by the surrounding CTR ECD residues, forming extensive hydrophobic contacts with W79 ECD and no direct interactions with either RAMP1 (AMY 1 R) or RAMP3 (AMY 3 R), again consistent with the restrictive interactions formed by Pro32 sCT with the CTR ECD

SS 31 For research use only

Glutathione and ROS staining of primary T and B cells Glutathione and ROS staining of human T and B cells was performed on freshly isolated mononuclear cells from peripheral blood or bone marrow samples from 7 control donors and 17 patients