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Monoclonal antibodies targeting the conserved PG portion (N-acetyl-L-isoglutamine) have been developed, which can specifically bind to PG (Huang et al., 2019)

Studies are planned to further evaluate NPI-001 and NPI-002 as potential treatments for AMD and Stargardt disease

Further exploration of the effects of sub-inhibitory concentrations of selected inhibitors, 30 M trifluoperazine and 20 M CGS 12066B, on engineered strains carrying maltose-inducible copies of one of three genes [cyclin hgc1 , transcription factor ume6 , MAPKK ste11 ], responsible for hyphal formation, revealed complete inhibition of morphogenesis induced by Ste11 and CaUme6 and partial inhibition induced by Hgc