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Science 301 , 17201725 (2003)

The possible therapeutic application of HGF and HGF mimetics for the treatment of neurological disorders is discussed

For example, in ATII-treated rats, inhibition of protein kinase C in vivo reduced blood pressure and vascular superoxide formation by inhibiting the activity and expression of Nox and by preventing eNOS uncoupling, 14 as well as sGC downregulation (unpublished observation)