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Similarly, in vitro evidence showed that lower levels of Sox2 activate the transcription of pluripotency genes, whereas higher levels of Sox2 repress it (Boer et al., 2007)

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demonstrated that intervention with Okra polysaccharides (OP) from Abelmoschus esculentus (L.) Moecnch suppressed the expression of TLR4, MyD88, and nuclear translocation of NF-B, suggesting that the TLR4/NF-B pathway may be involved in the mechanism of action of OP in the brain (Yan et al., 2020)