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For a break to lead to a retinal detachment, there usually must be accompanying changes in the vitreous gel, such as an increase in vitreous liquefaction, vitreous contraction, or sudden shifting of the vitreous from eye movement

Andersen A, Berge SR, Engeland A, Norseth T (1996) Exposure to nickel compounds and smoking in relation to incidence of lung and nasal cancer among nickel refinery workers