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[15] Likewise, studies associate youth hookah use with subsequent cigarette use, increased intensity of cigarette use, and decreased success in quitting

Fire-Cured: Dark Air-Cured: Due to their dense structure and strong aroma, these tobaccos are used sparingly and often require specific processing adjustments before use in modern tobacco machinery systems

Leaves of other nicotiana plants do contain nicotine, but bear in mind that they may also contain other compounds, such as anabasine, which is highly toxic to humans and animals