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This can lead to painful bloating, known as gastric distension, which in severe cases may cause gastric dilatation-volvulus (GDV): a life-threatening condition where the stomach twists on itself, cutting off blood flow

This means that under Australian law, it is illegal for nicotine pouches to be commercially sold, imported, or advertised as nicotine pouches are therapeutic goods

Tightly roll one edge of the pastry to the center

Risk of bias assessment Only one study was classified as having low risk of bias 27 , while nearly all studies 23-26,28-33 (10 out of 11) were judged to have a high risk of bias or poor quality, primarily due to the domain of outcome measurement (Supplementary file Tables 6 and 7)