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Keywords: High oxygen supplementation, kidney, reactive oxygen species, inter-organ communication Introduction Oxygen is one of the most ubiquitously used medical interventions in medicine

The expression of AANAT, the rate-limiting enzyme for melatonin synthesis, increases in the uterus during early pregnancy, and MT2 receptors are specifically expressed in uterine luminal epithelial cells and uterine glands on the second day of pregnancy (86)