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The conjugate base has been used as a nucleophile

C., Lopez, B

Guo Jun Qihuang Scholar Inheritance Studio, Ningxia Hui Autonomous Region Hospital of Traditional Chinese Medicine, Ningxia Hui Autonomous Region Academy of Traditional Chinese Medicine, Ningxia Hui Autonomous Region, China

The indole-3-carbinol is then proposed to interconvert to a reactive 3-methyleneindolenine intermediate that can react spontaneously with GSH to form a thiolated product ( 14 , with higher order di- tri- and tetra-sulfides forming through radical-enhanced disproportionation during the course of extraction