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doi: 10.1016/j.chom.2021.01.010 478 ZhangL.WangC.ChenK.ZhongW.XuY.MolnrI.et al

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J Clin Med 9:2329

The prominent lymphocytic inflammationat least in the earlier relapsing phase of the diseaseis traditionally thought to be the primary insult with immune cells recruited into the CNS to induce recurrent chronic injury (Box 1)