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Loss of function mutation in either Fas (lpr mice) or FasL (gld mice) leads to lymphadenopathy and splenomegaly as a result of decreased apoptosis in CD4-CD8- T lymphocytes
and CDK4 kinases through phosphorylation of a critical threonine residue in the T-loop of the CDK-cyclin complexes
Flt3L is produced by T cells and stromal fibroblasts
Immunogen: Recombinant protein of human MKS1
ACADS Polyclonal Antibody-BS8789 Intracellular delivery of antibodies Loss of function mutation inACADS Polyclonal Antibody Sizes: 50l, 100l Catalogue Numbers: BS8789 50, BS8789 100 Product: Rabbit IgG, 1mg ml in PBS with 0. 02% sodium azide, 50% glycerol, pH7. 2 Swiss Prot: P16219 Host: Rabbit Reactivity: Human, Mouse, Rat Applications: WB, IHC, IF All Applications: WB: 1: 500~1: 2000 IHC: 1: 50~1: 200 IF: 1: 50~1: 200 Background: This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl CoA dehydrogenase family.
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