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Includes: Measurement of oxidized and reduced glutathione levels Sample requirement: Serum Suitable for postal submission.

Aging and age-related diseases Aging is a universal, intrinsic, irreversible, heterogeneous and multidimensional process of progressive involution characterized by a gradual loss of physiological functions that increases the probability of death

Typical endpoints include lesion size reduction, mucosal histology, and markers of epithelial repair

Recently, the FDA approved omaveloxolone, a potent activator of Nrf2 signaling, as the first therapeutic agent for FRDA (392), marking a significant step toward targeting redox imbalance and ferroptosis in this disease