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Upon binding an ECM ligand, integrins transmit signals that activate a number of signaling pathways responsible for regulating actin-mediated processes (i.e phagocytosis, cell contractility, and fibronectin fibrillogenesis) that play an important role in regulating intraocular pressure (IOP) and may be involved in glaucoma

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Nicotinic acid prevents experimental liver fibrosis by attenuating the prooxidant process

Maatuf, Y., Kushnir, Y., Nemirovski, A., Ghantous, M., Iskimov, A., Binshtok, A