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A future vision of geriatric care could include personalized chronotherapy plans: timing of meals, light exposure, exercise, and possibly melatonin administration tailored to each individuals circadian profile, measured via wearable circadian phase monitors ( On the research front, several questions remain

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66 , e0239521 (2022)

These findings demonstrate the effect of hypoxia on the post-translational modifications of histones in the regulation of proteins involved in the maintenance of the BBB structure and that these mechanisms may be determining the dysfunction of the BBB induced by the hypoxia