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GLP-1 therapy is not a shortcutit is a biological intervention designed to correct underlying metabolic dysfunction

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With the lung infiltration of neutrophils and macrophages triggered by CS, proinflammatory cytokines such as interleukin -1(IL-1) and tumor necrosis factor- (TNF-) induce a cascade of amplification effects of inflammation, and activate nuclear factor- B (NF- B) (Di Stefano et al., 2002)

Peng K-Y, Watt MJ, Rensen S et al (2018) Mitochondrial dysfunction-related lipid changes occur in nonalcoholic fatty liver disease progression