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Development of eosinophil peroxidase activity and concomitant alteration of the antioxidant defenses on the liver of mice infected with Schistosoma mansoni

The first study (ALA in Diabetic Neuropathy Study) enrolled 328 patients with symptomatic peripheral neuropathy and non-insulin-dependent diabetes mellitus who were randomized to receive an intravenous infusion of ALA at three different doses (1200 mg, 600 mg, or 100 mg/day) or a placebo for a period of 3 weeks