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These studies confirm its safety for topical applications

Platelets 31 , 627632 (2020)

However, it is critical to note that no human clinical trials have been published, and the safety and efficacy of 5-Amino-1MQ in humans remain unknown

Researchers in Greece showed that a large group of people who had side effects from isotretinoin got better when taking L-carnitine compared to those who took a placebo