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For example, a tobacco user may reach for a dip from their can of snuff

Smokers were not receiving the same nicotine satisfaction and therefore began to compensate for the reduction in nicotine by smoking more cigarettes, thus increasing their health risk. 2 These earlier studies were conducted on combustible cigarettes with significantly higher levels of nicotine than the VLN products

Researchers found evidence of reduced motivation in adolescent cannabis users, and that those who used cannabis early demonstrated poorer performance on tasks of sustained attention, impulse control, and executive functioning. Researchers also found that subjects who started using cannabis before the age of 15 showed significant impairment in reaction times, whereas users who abstained until after the age of 15 were not affected