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The team defined heavy smoking as 20 cigarettes a day for 15 years.Overall, smoking was estimated to be responsible for more than a third of insulin-resistant type 2 diabetes cases, researchers said.The strongest association was seen for the subtype characterized by severe insulin resistance (SIRD), which suggests that smoking may contribute to diabetes by impairing the bodys ability to respond to insulin, Keysendal said.Results also showed that people with a high genetic risk for impaired insulin secretion were more than three times as likely to develop SIRD.Our findings emphasize the importance of smoking cessation in the prevention of type 2 diabetes, Keysendal said

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