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414 A recent review of the evidence found that most studies examining subjective cognitive decline as an outcome showed higher prevalence among SGM older adults, while those examining objective measures of cognitive performance showed more mixed results

This algorithm extends the pebble game algorithm to predict whether local perturbation of rigidity at one site of the protein, transmit across the structure to change the rigidity of the second distant site

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doi:10.1186/s13023-022-02179-y