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doi: 10.3390/ijms22073789 75 DabravolskiSANikiforovNGEidAHNedosugovaLVStarodubovaAVPopkovaTVet al

It plays a role in metabolism of amino acids and is a necessary co-factor in the folate cycle, lack of which can lead to anemia

In conclusion, non-pharmacological therapies that focus on controlling the etiology of liver disease, improving nutrition, increasing muscle mass, mitigating triggers and risk factors, and enhancing coping mechanisms are significantly more effective in combating fatigue in cirrhosis compared to pharmacological treatments (Figure 2) (4, 9)