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The most significant CGA in coffee, 5CQA, has the ability to neutralize peroxynitrite (ONOO), superoxide anions (O 2 ), hydroxyl radicals (OH), and 1,1diphenyl2picrylhydrazyl radicals (DPPH

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(2019) performed a randomized controlled trial involving 56 women with PCOS, revealing a decrease in hirsutism, total testosterone, hs-CRP, and MDA, alongside an increase in TAC and total GSH among participants administered 5 g of melatonin twice daily for 12 weeks, in contrast to the placebo group [186]

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