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In contrast, T2D is characterized by insulin resistance along with relative insufficiency in its secretion due to factors such as obesity, sedentary lifestyle, or genetic predisposition [29]

doi: 10.1016/S0140-6736(08)61525-1

1,25-Dihydroxyvitamin D3 restores fertility of vitamin D-deficient female rats

Additionally, if your gastrointestinal tract does not function normally, as with celiac disease or Crohns disease, you may have trouble absorbing or releasing vitamin B12, which will affect the levels in your body and how long the vitamin stays there